Baki, a great grappler needs to live up to his name being the son of the the greatest grapplers of all time: Hanma Yujiro. At the Shinshinkai Organization's private arena, anything goes and the odds are always stacked against you. Current champion of the urderground tournament he fight to defend his title against the worlds strongest and best martial artists, including "the beast" his own father Yujiro.
Tadayasu Sawaki was born with an unique ability: He can see and communicate with bacteria and other micro-organisms - in fact they consider him to be their friend and are quite noisy. Together with his childhood friend, Kei, he starts a new year off as a first-year student at an Agricultural College. But none of his experiences so far could prepare him for college life!! As this is an \'educational\' anime series, the last 90 seconds of each episode is devoted to a \'microbe theater\' which has various micro-organisms explain who they are and what they do.